UB - University at Buffalo, The State University of New York UB Mechanical and Aerospace Engineering

Bioengineering

Bioengineering

Faculty

Affiliated Faculty

Laboratories

Research Summaries

Cardiovascular Flows/Devices
Cardiovascular disease is the number one cause of death in the US, and state-of-the-art simulations can play and important role in diagnosis, patient care planning, virtual surgery, and device design and optimization. We have developed computational tools for patient-specific, image-based numerical simulations of cardiovascular flows and devices. The computational tools have been applied to simulate left-ventricular flows, intracranial aneurysms, and mechanical and bioprosthetic heart valves. A sample of simulation videos can be found here

 

Image-Based Computational Fluid Dynamics Simulations for Intracranial Aneurysms

At the Hemodynamics and Vascular Biology Lab at the Toshiba Stroke & Vascular Research Center, we aim at understanding pathophysiology of intracranial aneurysms and improving their diagnosis and treatment, by combining computational fluid dynamics (CFD) and engineering design with medical imaging and molecular biology techniques. We analyze aneurysm rupture risk, evaluate endovascular device for stroke intervention, and develop patient-specific image-based computational fluid dynamics and FEM analysis tools to provide both rapid clinical input and in-depth mechanistic understanding. We also employ in vivo and in vitro bioengineering model systems to study flow-mediated vascular responses and aneurysm pathogenesis.

H. MENG. Sponsors: NIH/NINDS, Toshiba Medical Systems, Covidien.

 
Hemodynamic Stresses and Pathogenesis of Intracranial Aneurysms

At the Hemodynamics and Vascular Biology Lab at the Toshiba Stroke & Vascular Research Center, we aim at understanding pathophysiology of intracranial aneurysms and improving their diagnosis and treatment, by combining computational fluid dynamics (CFD) and engineering design with medical imaging and molecular biology techniques. We analyze aneurysm rupture risk, evaluate endovascular device for stroke intervention, and develop patient-specific image-based computational fluid dynamics and FEM analysis tools to provide both rapid clinical input and in-depth mechanistic understanding. We also employ in vivo and in vitro bioengineering model systems to study flow-mediated vascular responses and aneurysm pathogenesis.

H. MENG. Sponsors: NIH/NINDS, Toshiba Medical Systems, Covidien.

 

Development of bio-inspired robots
Our research in this area is exploring new image guided and semi-autonomous robotic technologies to access and perform surgical procedures. For example a new robotic system developed in our lab can be tele-manipulated remotely to insert guide wires and catheters to remote areas of the brain to treat stroke patients. We completed the first prototype of the patent pending tele-robotic framework called System for Endovascular Tele-robotic Access (SETA) in 2010. Our second generation robot is undergoing trials at the Department of Neurosurgery at UB. We are also exploring assistive co-robotic technology in wide range of micro-surgery procedures.

T. KESAVADAS

 

Medical Simulation

Our research looks at developing new hardware and software to simulate complex medical procedures such as robotic surgery, neuro-endovascular surgery, trocar insertion procedure and intubation training. Systems developed here are currently in use in many US and European medical colleges.

 

T. KESAVADAS

 

  • UB MAE Research

    Research Spotlight

    MAE researchers have developed advanced computational techniques for Fire Simulation and multi-phase reacting turbulent flows.

  • MAE

    Research Spotlight

    UB MAE researchers in computational mechanics have developed a high fidelity volcanic landslide simulator to aid geologists in mapping the hazard areas at locations such as the island of Montserrat.

  • UB MAE Research

    Research Spotlight

    A Level Set Embedded Interface Method has been developed at Compuational Fluid Dynamics Laboratory to simulate Conjugate heat transfer for irregular geometries

  • UB MAE Research

    Research Spotlight

    MAE's Laser Flow Diagnostic Laboratory is a leader holographic particle image velocimetry, a three-dimensional, next generation flow diagnostics tool.

  • UB MAE Research

    Research Spotlight

    MAE's Automation, Robotics, and Mechatronics Laboratory is conducting research both on the theoretical formulation and experimental validation of such novel mechatronic systems as multi-robot collaboration.

  • UB MAE Research

    Research Spotlight

    The nonlinear estimation group is developing techniques for propagating uncertainties through nonlinear dynamical systems for better forecasting and output uncertainty characterization.

  • UB MAE Research

    Research Spotlight

    Study of Non-premixed flame-wall interaction using vortex ring configuration is done for the first time at the Computational Fluid Dynamics Laboratory.

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